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1.What is the Ondansetron ?
It is crystallized from methanol, mp 231-232 ℃. Ondansetron hydrochloride dihydrate : C18H19N3O·ClH·2H2O[99614-01-4]. From the water-isopropanol ,? white crystalline solid is generated, mp 178.5~179.5 ℃. Ondansetron Hydrochloride Monohydrate: C18H19N3O·HCl·H2O. Crystallization, melting point? 186~187 ℃. 3S-type: [α] D25-14 ° (C = 0.19, methanol). 3R-type: [α] D24 + 16 ° (C = 0.34, methanol).
Ondansetron (hydrochloride) (CRM) (Item No. 21710) is a certified reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.
2.What is the CAS number for Ondansetron ?
The CAS number of Ondansetron is 99614-02-5.
3.What are another words for Ondansetron ?
Synonyms?for?Ondansetron 99614-02-5:1,2,3,4-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-9H-carbazol-4-one;GR 38032;GR 38032X;Ondanles;1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1h-imidazol-1-yl)methyl)-4h-carbazo;Zofran;Zophren;Zudan;
4.What is Ondansetron (99614-02-5) used for?
Used in Pharmaceutical Industry:
Ondansetron is used as an antiemetic agent for the prevention and treatment of nausea and vomiting caused by various conditions such as chemotherapy, radiation therapy, and surgery. It helps to control the symptoms by blocking the action of serotonin, a neurotransmitter that can trigger vomiting.
Used in Research and Forensic Applications:
Ondansetron is used as a certified reference material in research and forensic applications. It serves as a standard for the development, validation, and quality control of analytical methods and procedures related to the detection and quantification of ondansetron in biological samples.
Used in Alcoholism Treatment:
Ondansetron is used as a therapeutic agent for reducing alcohol consumption and mood disturbances in early-onset alcoholics. It has been found to be effective in reducing the desire to drink alcohol and improving mood-related symptoms in individuals with alcohol use disorder.
Ondansetron (Zofran) is potent antagonists of 5-HT3 receptors,which is found peripherally on vagal nerve terminals and centrally in the CTZ. During chemotherapy that induces vomiting, mucosal enterochromaffin cells in the GI tract release serotonin, which stimulates 5-HT3 receptors.
InChI:InChI=1/C17H18N4O/c1-12-18-8-10-20(12)11-21-9-7-15-16(17(21)22)13-5-3-4-6-14(13)19(15)2/h3-6,8,10H,7,9,11H2,1-2H3
Relevant articles related to Ondansetron:
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Article |
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C(sp2)-H Bond Multiple Functionalization in Air for Construction of Tetrahydrocarbazoles with Continuous Quaternary Carbons and Polycyclic Diversification |
Dong, Suzhen,Jia, Shikun,Liu, Shunying,Ni, Dan,Pi, Rou,Song, Longlong,Tang, Jie,Yang, Fan supporting information, (2020/03/04) |
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Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom |
- Page/Page column 8, (2008/06/13) |
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A ONE-POT PROCESS FOR THE PREPARATION OF ANTIEMETIC AGENT, 1,2,3,9-TETRAHYDRO-9-METHYL-3[(2-METHYL)-1H-IMIDAZOLE-1-YL)METHYL]-4H-CARBAZOL-4-O |
- Page/Page column 18-19, (2008/06/13) |
5.Buy Ondansetron with the best price .
Jiangxi Lixin Pharmaceutical Co.,Ltd. is a quality supplier of Ondansetron. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Ondansetron 99614-02-5.