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Manufacturer supply high quality Furan-2-carbohydrazide 3326-71-4 with GMP standards
- Molecular Formula: C5H6N2O2
- Molecular Weight: 126.115
- Appearance/Colour: Beige crystals
- Melting Point: 77-79 °C(lit.)
- Refractive Index: 1.535
- Boiling Point: 279°C(lit.)
- PKA: 12.18±0.10(Predicted)
- PSA: 68.26000
- Density: 1.264 g/cm3
- LogP: 0.97430
Furan-2-carbohydrazide(Cas 3326-71-4) Usage
InChI:InChI=1/C5H6N2O2/c6-7-5(8)4-2-1-3-9-4/h1-3H,6H2,(H,7,8)
3326-71-4 Relevant articles
Phosphine-free ruthenium complex-catalyzed synthesis of mono- Or dialkylated acyl hydrazides via the borrowing hydrogen strategy
Joly, Nicolas,Bettoni, Léo,Gaillard, Sylvain,Poater, Albert,Renaud, Jean-Luc
, p. 6813 - 6825 (2021/05/29)
Herein, we report a diaminocyclopentadie...
N-acylhydrazones confer inhibitory efficacy against New Delhi metallo-β-lactamase-1
Gao, Han,Li, Jia-Qi,Kang, Peng-Wei,Chigan, Jia-Zhu,Wang, Huan,Liu, Lu,Xu, Yin-Sui,Zhai, Le,Yang, Ke-Wu
, (2021/07/07)
The expression of β-lactamases, especial...
Ruthenium-Catalyzed Three-Component Alkylation: A Tandem Approach to the Synthesis of Nonsymmetric N,N-Dialkyl Acyl Hydrazides with Alcohols
Bettoni, Léo,Joly, Nicolas,Lohier, Jean-Fran?ois,Gaillard, Sylvain,Poater, Albert,Renaud, Jean-Luc
supporting information, p. 4009 - 4017 (2021/07/02)
The borrowing hydrogen strategy has been...
Design, synthesis, in vitro and in vivo evaluation against MRSA and molecular docking studies of novel pleuromutilin derivatives bearing 1, 3, 4-oxadiazole linker
Liu, Jie,Zhang, Guang-Yu,Zhang, Zhe,Li, Bo,Chai, Fei,Wang, Qi,Zhou, Zi-Dan,Xu, Ling-Ling,Wang, Shou-Kai,Jin, Zhen,Tang, You-Zhi
, (2021/05/17)
A class of pleuromutilin derivatives con...
3326-71-4 Process route
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1006894-82-1
N'-[benz-(E)-ylidene]furan-2-ylcarbohydrazide
-
-
3326-71-4
2-furoic acid hydrazide
-
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100-52-7
benzaldehyde
| Conditions | Yield |
|---|---|
|
With
water;
In
ethanol;
pH=2.47;
Rate constant;
Phosphoric acid buffer;
|
|
|
With
water;
In
ethanol;
pH=4.48;
Rate constant;
Citric acid buffer;
|
-
-
527-69-5
2-furancarbonyl chloride
-
-
3326-71-4
2-furoic acid hydrazide
| Conditions | Yield |
|---|---|
|
With
pyridine; hydrazine;
In
tetrahydrofuran;
at 0 - 50 ℃;
for 2h;
|
|
|
Multi-step reaction
with
2
steps
1: Reflux
2: hydrazine hydrate
With
hydrazine hydrate;
|
|
|
Multi-step reaction
with
2
steps
1: triethylamine / 1 h / 20 °C / Inert atmosphere
2: hydrazine hydrate / methanol / 3 h / Reflux
With
hydrazine hydrate; triethylamine;
In
methanol;
|
|
|
2-furancarbonyl chloride;
With
triethylamine;
In
methanol;
for 1h;
Inert atmosphere;
With
hydrazine hydrate;
In
methanol;
for 3h;
Reflux;
|
|
|
With
hydrazine hydrate;
In
methanol;
at 65 ℃;
for 4h;
|
|
|
With
hydrazine hydrate; triethylamine;
In
methanol;
at 65 ℃;
for 4h;
|
3326-71-4 Upstream products
-
614-99-3
Ethyl 2-furoate
-
88-14-2
2-furanoic acid
-
611-13-2
2-furoic acid methyl ester
-
1006894-82-1
N'-[benz-(E)-ylidene]furan-2-ylcarbohydrazide
3326-71-4 Downstream products
-
37961-96-9
furan-2-carboxylic acid N'-(furan-2-ylmethylene)hydrazide
-
104557-30-4
2-acetylfuran-2-furoylhydrazone
-
103418-56-0
5-(furan-2-yl)-1,3,4-oxadiazol-2(3H)-one
-
99973-15-6
[1,4]benzoquinone-(furan-2-carbonylhydrazone)-oxime