DOTA

CAS No.: 60239-18-1

product details:

Purity: 99%

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1.What is the DOTA ?

Colourless crystals

ChEBI: An azamacrocyle in which four nitrogen atoms at positions 1, 4, 7 and 10 of a twelve-membered ring are each substituted with a carboxymethyl group.

DOTA, or 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, is a macrocyclic complexing agent that forms a twelve-membered ring with four nitrogen atoms at positions 1, 4, 7, and 10, each substituted with a carboxymethyl group. It is known for its ability to chelate various metal ions, making it a versatile compound in the fields of medical imaging, diagnostics, and therapeutics. DOTA exists as colorless crystals.

2.What is the CAS number for DOTA ?

The CAS number of DOTA is 60239-18-1.

3.What are another words for DOTA ?

Synonyms?for?DOTA 60239-18-1:1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane;1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid;DOTA;NSC681107;Tetraxetan;

4.What is DOTA (60239-18-1) used for?

1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is a macrocyclic complexing agent.It has been used for radiolabeling of carbon nanotube bioconjugates by chelating 64Cu radioisotope.DOTA can be activated with N-hydroxysulfosuccinimidyl for conjugation with monoclonal antibodies in clinical radioimmunotherapy.It can form complexes with gadolinium for application as MRI contrast agents.Metal complexes of DOTA-peptide conjugates can be used as therapeutic radiopharmaceuticals.

InChI:InChI=1/C16H28N4O8/c21-13(22)9-17-1-2-18(10-14(23)24)5-6-20(12-16(27)28)8-7-19(4-3-17)11-15(25)26/h1-12H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28)

Relevant articles related to DOTA:

Article

Source

Cherenkov Radiation-Mediated In Situ Excitation of Discrete Luminescent Lanthanide Complexes

Cosby, Alexia G.,Ahn, Shin Hye,Boros, Eszter

, p. 15496 - 15499 (2018)

METHOD FOR PREPARING 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID

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Paragraph 0129; 0130, (2020/12/01)

Method for preparing contrast agent

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Paragraph 0005; 0058-0061, (2020/07/24)

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